Publications
 
 

Reviews

Webb, S.E., and Miller, A.L. (2013). Calcium signalling in extra-embryonic domains during early teleost development. Int. Rev. Cell and Molecular Biol. 304: 369-418.

Webb, S.E. and Miller, A.L. (2013). Ca2+ signaling during activation and fertilization in the eggs of teleost fish. Cell Calcium Special Edition 53:24-31. [PubMed]

Webb, S.E. and Miller, A.L. (2012). Aequorin-based genetic approaches to visualize Ca2+ signaling in developing animal systems. Biochim. Biophys. Acta. 1820(8):1160-8. doi: 10.1016/j.bbagen.2011.12.008. [PubMed]

Webb, S.E., Fluck, R.A., Miller, A.L. (2011) Calcium signaling during the early development of medaka and zebrafish. Biochimie. 93(12):2112-25. [PubMed]

Miller, A.L. (2010). Calcium signaling during the early meroblastic cleavages of zebrafish and medaka embryos. Front. Biol. 5(4): 283-285.

Moreau, M., Néant, I., Webb, S.E., Miller, A.L. and Leclerc, C. (2008) Calcium signaling during neural induction in Xenopus laevis embryos.Phil. Trans. R. Soc. B. 363:1371-1375. [online access]

Webb, S.E., Li, W.M. and Miller, A.L. (2008) Calcium signaling during the cleavage period of zebrafish development. Phil. Trans. R. Soc. B. 363:1363-1369. [online access]

Webb, S.E. and Miller, A.L. (2007). Ca2+ signaling and early embryonic patterning during zebrafish development.Proceedings of the Australian Physiological Society. 38:43-51. [online access]

Webb, S.E. and Miller, A.L  (2006). Ca2+ signaling and early embryonic patterning during the Blastula and Gastrula Periods of Zebrafish and Xenopus development  Biochim. Biophys. Acta. 1763:1192-1208. [PubMed]

Leclerc, C., Néant, I., Webb, S.E., Miller, A.L. and Moreau, M. (2006). Calcium transients and calcium signalling during early neurogenesis in the amphibian embryo Xenopus laevis.  Biochim. Biophys. Acta. 1763:1184-1191. [PubMed]

Webb, S.E. and Miller, A.L.  (2006). Ca2+ signaling during vertebrate somitogenesis.  Acta Pharmacol. Sin.  27:781-790. [PubMed]

Webb, S.E., Moreau, M. Leclerc, C. and Miller, A.L. (2005).  Calcium transients and neural induction in vertebrates.  Cell Calcium 37:375-85. [PubMed]

Webb, S.E. and Miller, A.L. (2003).  Calcium signalling during embryonic development.  Nature Reviews Molecular Cell Biology 4: 539-551. [PubMed]

Webb, S.E., Moreau, M., Leclerc, C. and Miller, A.L. (2001).  Calcium in development: from ion transients to gene expression.  Bioessays 23(4): 372-374. [PubMed]

Webb, S.E. and Miller, A.L. (2000). Calcium signalling during zebrafish embryonic development. Bioessays 22(2): 113-123. [PubMed]

 

 

Book Chapters

Webb, S.E. and Miller, A.L. (2017). Ca2+ signalling and membrane dynamics during cytokinesis in animal cells. Invited Chapter for: Membrane Dynamics and Ca2+ Signalling (Springer) - submitted.

Webb, S.E., Chan, C.M. and Miller, A.L. (2013). Introduction of aequorin into zebrafish embryos for recording Ca2+ signaling events during the first 48 hours of development. Cold Spring Harbor Protocols, CHS Press, Ed. Jan Payrs. 1-4, doi:10.1101/pdb.top066316.

Webb, S.E., and Miller, A.L. (2013). Microinjecting holo-aequorin into dechorionated and intact zebrafish embryos. Cold Spring Harbor Protocols, CHS Press, Ed. Jan Payrs. 1-9, doi:10.1101/pdb.top072967. 3.

Chan, C.M., Miller, A.L. and Webb, S.E. (2013). Reconstitution of holo-aequorin with apoaequorin mRNA and coelenterazine in zebrafish embryos. Cold Spring Harbor Protocols, CHS Press, Ed. Jan Payrs. 1-5, doi:10.1101/pdb.top072975.

Webb, S.E. and Miller, A.L. (2010). Visualization of Ca2+ signaling during embryonic skeletal muscle formation in vertebrates. Eds. Berridge, M.J., Putney, J., Roderick, L., Bootman, M.D. Cold Spring Harbor Perspectives in Biology, CHS Press. doi:101101/cshperspect.a004325. [online access]

Webb, S.E., Rogers, K.L, Karplus, E. and Miller, A.L. (2010). The use of aequorins to record and visualize Ca2+ dynamics: From subcellular microdomains to whole organisms. In: A Practical Guide to the Study of Calcium in Living Cells. (Ed. M. Whitaker). Methods in Cell Biology. 99:263-300. [online access]

Moreau, M., Webb, S.E., Néant, I., Miller, A.L. and Leclerc, C. (2009). Calcium signaling and cell fate determination during neural induction in amphibian embryos. Handbook of Neurochem. Mol. Neurobiol (Ed. K. Mikoshiba). Ch. 1 pp. 3-13. Springer Science+Business Media, LLC. [online access]

Webb, S.E. and Miller, A.L.  (2007).  Ca2+ signaling during embryonic cytokinesis in animal systems.  In: New Comprehensive Biochemistry vol 41: Calcium.  A Matter of Life or Death.  (Eds. J. Krebs & M. Michalak). Elsevier. Ch.17 pp.445-470. [online access]

Dodd, A., Greenwood, D.R., Miller, A.L. Webb, S.E., Chambers, S.P., Copp, B.R. and Love, D.R.  (2006). Zebrafish: At the nexus of functional and chemical genomics. Biotech. Gen. Eng. Rev.  22:77-99. [PubMed]

Miller, A. L., Karplus, E. and Jaffe, L. F. (1994). Use of aequorin for [Ca2+] imaging. Chapter 13. In: Methods in Cell Biology Volume 40: A Practical Guide to the Study of Ca2+ in Living Cells (R. Nuccitelli ed.), pp. 305-338. Academic Press. [PubMed]

 

 

Research Papers

Kelu, J.J., Webb, S.E., Parrington, J., Galione, A. and Miller, A.L. (2017). Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos. Dev. Biol. 425:109-129.

Li W.M., Chan, C.M., Miller, A.L. and Lee, C.H. (2017). Dual functional roles of molecular beacon: a microRNA detector and inhibitor. J. Biol. Chem. Doi: 10.1074/jbc.M116.765776.

Hao, B., Wei, W., Webb, S.E., Miller, A.L., and Yue, J. (2017). The role of Ca2+ signaling in the differentiation of embryonic stem cells (ESCs) into cardiomyocytes. Frontiers in Stem Cell and Regenerative Medicine Research Vol 4. Doi: 10.2174/97816810843501170401.

Chan, C.M., Aw, J.T.M., Webb, S.E., Miller, A.L. (2016). SOCE proteins, STIM1 and Orai1, are localized to the cleavage furrow during cytokinesis of the first and second cell division cycles in zebrafish embryos. Zygote 24:880-889.

Chan, H.Y.S., Cheung, M.C., Gao, Y., Miller, A.L., and Webb, S.E. (2016). Expression and reconstitution of the bioluminescent Ca2+ reporter aequorin in human embryonic stem cells, and exploration of the presence of functional IP3 and ryanodine receptors during the early stages of their differentiation into cardiomyocytes. SCIENCE CHINA Life Sciencesdoi: 10.1007/s11427-016-5094-6.

Leclerc, C., Haeich, J., Aulestia, F.J., Kilhoffer, M.-C., Miller, A.L., Néant, I., Webb, S.E., Schaeffer, E., Junier, M.-P., Chneiweiss, H., and Moreau, M. (2016). Calcium signaling orchestrates glioblastoma development: Facts and conjectures.Biochim. Biophys. Acta Mol. Cell Res. 1863: 1447-1459.

Hao, B., Webb, S.E., Miller, A.L., and Yue, J. (2016). The role of Ca2+ signaling on the self-renewal and neural differentiation of embryonic stem cells (ESCs). Cell Calcium 59: 67-74.

Chan, C.M., Chen, Y., Hung, T.S., Miller, A.L. and Webb, S.E. (2015). Inhibition of SOCE disrupts cytokinesis in zebrafish embryos via inhibition of cleavage furrow deepening. Int. J. Dev. Biol. 59: 289-301.

Kelu, J.K., Chan, H.L.H., Webb, S.E., Cheng, A.H.H., Ruas, M., Parrington, J., Galione A., and Miller, A.L. (2015). Two-pore channel 2 activity is required for slow muscle cell-generated Ca2+ signaling during myogenesis in intact zebrafish. Int. J. Dev. Biol. 59: 313-325.

Moreau, M., Néant, I., Webb, S.E., Miller, A.L., Riou, J.-F., Leclerc, C. (2015). Ca2+ coding and decoding strategies for the specification or neural and renal precursor cells during development. Cell Calcium. 59: 75-83.

Chan, H.Y.S., Keung, W., Li, R.A., Miller, A.L. and Webb, S.E. (2015) Morphometric analysis of human embryonic stem cell-derived ventricular cardiomyocytes: Determining the maturation state of a population by quantifying parameters in individual cells. Stem Cells Int. Article ID 586908, 13 pages, doi:10.1155/2015/586908.

Barnes, M., van Rensburg, G., Li, W.-M., Mehmood, K., Mackedenski, S., Chan, C.-M., King, D.T., Miller, A.L. and Lee, C.H. (2015) Molecular insights into the coding region determinant-binding protein-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains. J. Biol. Chem. 290:625-639.

Webb, S.E., Goulet, C., Chan, C.M., Yuen, Y.F., and Miller, A.L. (2014). Biphasic assembly of the contractile apparatus during the first two cell division cycles in zebrafish embryos. Zygote. 22:218-228.

Yuen, M.Y.F., Webb, S.E., Chan, C.M., Thisse, B., Thisse, C. and Miller, A.L. (2013). Characterization of Ca2+ signaling in the external yolk syncytial layer during the late blastula and early gastrula periods of zebrafish development.  BBA Molecular Cell Research 1833:1641-1656. [PubMed]

Webb, S.E., Goulet, C., Chan, C.M., Yuen, Y.F. and Miller, A.L. (2013). Biphasic assembly of the contractile apparatus during the first two cell division cycles in zebrafish embryos. Zygote 27:1-11. [PubMed]

Webb, S.E., Cheung, C.Y., Chan, C.M., Love, D.R. and Miller, A.L. (2012). The application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca2+-signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions. Clin. Exp. Pharmacol. Physiol. 39:78-86. [PubMed]

Webb, S.E., Cheung, C.Y., Chan, C.M., Love, D.R. and Miller, A.L. (2011). The application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca2+-signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions. Proc. Aust. Physiol. Pharmacol. Soc. 42:29-40.

Zhang, J., Webb, S.E., Ma, L.H., Chan, C.M. and Miller, A.L. (2011). Necessary role for intracellular Ca2+ transients in initiating the apical-basolateral thinning of enveloping layer cells during the early blastula period of zebrafish development. Dev. Growth Diff. 53:679-696. [PubMed]

Cheung, C.Y., Webb, S.E., Love, D.R. and Miller, A.L. (2011). Visualization, characterization and modulation of Calcium signaling during the development of slow muscle cells in intact zebrafish embryos. Int. J. Dev. Biol. 55:153-174. [PubMed]

Mei, W., Lee, K.W., Marlow, F., Miller, A.L. and Mullins, M.C. (2009). hnRNP I/brom bones is required for calcium-mediated egg activation in the zebrafish. Development 136:3007-3017. [PubMed]

Leung, C.F., Miller, A.L., Korzh, V., Chong, S.W., Sleptosva-Freidrich, I. and Webb, S.E. (2009). Visualization of stochastic Ca2+ signals in the formed somites during the early Segmentation Period in intact, normally developing zebrafish embryos. Dev. Growth Differ. 51:617-637. [PubMed]

Lam, P.Y., Webb, S.E., Leclerc, C., Moreau, M. and Miller, A.L. (2009). Inhibition of stored Ca2+ release disrupts convergence-related cell movements in the lateral intermediate mesoderm resulting in abnormal positioning and morphology of the pronephric anlagen in intact zebrafish embryos. Dev. Growth Differ. 51:429-442. [PubMed]

Ma, L.H., Webb, S.E., Chan, C.M., Zhang, J. and Miller, A.L. (2009) Establishment of a transitory dorsal-biased window of localized Ca2+ signaling in the superficial epithelium following the mid-blastula transition in zebrafish embryos. Dev. Biol. 327:143-157. [PubMed]

Leclerc, C., Webb, S.E., Miller, A.L., Moreau, M. (2008). An increase in intracellular Ca2+ is involved in pronephric tubule differentiation in the amphibian Xenopus laevis. Dev. Biol. 321:357-367. [PubMed]

Li, W.M., Webb, S.E., Chan, C.M. and Miller, A.L. (2008). Multiple roles of the furrow deepening Ca2+ transient during cytokinesis in zebrafish embryos. Dev. Biol. 316:228-48. [PubMed]

Montaville, P. Dai, Y., Cheung, C., Giller, K., Becker, S., Michalak, M., Webb, S.E. Miller, A.L. and Krebs, J.  (2006).  Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.  Biochim. Biophys. Acta. 1763:1335-1343. [PubMed].

Li, W.M., Webb, S.E., Lee, K.W. and Miller, A.L.  (2006).  Recruitment and SNARE-mediated fusion of vesicles in furrow membrane remodeling during cytokinesis in zebrafish embryos.  Exp. Cell. Res. 312:3260-3275. Link repairing [PubMed]

Cheung, Y.C., Webb, S.E. and Miller, A.L. (2006). Transient expression of apoaequorin in zebrafish embryos: extending the ability to image calcium transients during later states of development. Int. J. Dev. Biol. 50:561-569 [online access]

Lee, K.W., Webb, S.E. and Miller A.L.  (2006).  Requirement for a localized IP3R generated Ca2+ transient during the furrow positioning process in zebrafish zygotes. Zygote 14: 143-155. [PubMed]

Lee, K.W., Ho, S.M., Wong, C.H., Webb, S.E. and Miller, A.L. (2004).  Characterization of mid-spindle microtubules during furrow positioning in early cleavage period zebrafish embryos.  Zygote 12: 221-30.  [PubMed]

Cheng, J.C., Miller, A.L. and Webb, S.E. (2004). Organisation and function of microfilaments during late epiboly in zebrafish embryos.  Developmental Dynamics 231: 313-323. [PubMed]

Chan, C., Harland, M.L., Webb, S.E., Chen, J., Miller, A.L. and Barritt, G.J. (2004).  Evaluation, using targeted aequorins, of the roles of the endoplasmic reticulum  and its (Ca2+ + Mg2+)ATP-ases in the activation of store-operated channels in liver cells.  Cell Calcium 35: 317-331. [PubMed]

Lee, K.W., Webb, S.E. and Miller, A.L. (2003).  Ca2+ released via IP3 receptors is required for furrow deepening during cytokinesis in zebrafish embryos.  Int. J. Dev. Biol.  47: 411-421. [PubMed]

Leclerc, C., Lee, M., Webb, S.E., Moreau, M. and Miller, A.L.  (2003). Calcium transients triggered by planar signals induce the expression of Zic3 during neural induction in Xenopus. Developmental Biology 261(2): 381-390. [PubMed]

Webb, S.E. and Miller, A.L.  (2003).  Imaging intercellular calcium waves during late epiboly in intact zebrafish embryos.  Zygote 11(2): 175-182. [PubMed]

Leclerc, C., Webb, S.E., Daguzan, C., Moreau, M. and Miller, A.L. (2000). Imaging patterns of calcium transients during neural induction in Xenopus laevis embryos. J. of Cell Sci. 113: 3519-3529. [PubMed]

Leung, C.F., Webb, S.E. and Miller, A.L. (2000).  On the mechanism of ooplasmic segregation in single-cell zebrafish embryos. Development, Growth & Differentiation 42(1): 29-40. [PubMed]

Lee, K.W., Webb, S.E. and Miller, A.L. (1999). A wave of free cytosolic calcium traverses zebrafish eggs on activation. Developmental Biology 214: 168-180. [PubMed]

Gilland, E., Miller, A.L., Karplus, E., Baker, R. and Webb, S.E. (1999). Imaging of multicellular large-scale rhythmic calcium waves during zebrafish gastrulation. PNAS 96: 157-161. [PubMed]

Fluck, R., Abraham, V., Miller, A. and Galione, A. (1999).  Microinjection of cyclic ADP-ribose triggers a regenerative wave of Ca2+ release and exocytosis of cortical alveoli in medaka eggs. Zygote 7(4): 285-292. [PubMed]

Leung, C.F., Webb, S.E. and Miller, A.L. (1998). Calcium transients accompany ooplasmic segregation in zebrafish embryos. Development, Growth & Differentiation 40 (3): 313-326. [PubMed]

Webb, S.E., Lee, K.W., Karplus, E. and Miller, A.L. (1997). Localized calcium transients accompany furrow positioning, propagation, and deepening during the early cleavage period of zebrafish embryos. Developmental Biology 192: 78-92. [PubMed]

Lee, K.W., Baker, R., Galione, A., Gillard, E.H., Hanlon, R.T. and Miller, A.L. (1996). Ionophore-induced calcium waves activate unfertilized zebrafish (Danio rerio) eggs. Biological Bulletin 191: 265-267.

Browne, C.L., Créton, R., Karplus, E., Mohler, P.J., Palazzo, R.E. and Miller, A.L. (1996). Analysis of the calcium transient at NEB during the first cycle in dividing sea urchin eggs. Biological Bulletin 191: 5-16. [PubMed]

Eckberg, W. R. and Miller, A. L. (1995). Propagated and non-propagated calcium transients during egg activation in the annelid Chaetopterus. Developmental Biology 172: 654-664.

Cubbit, A. B., Firtel, R. A., Fischer, G., Jaffe, L. F., Karplus, E. and Miller, A. L. (1995). Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin. Development 121: 2291-2301. [PubMed]

Abraham, V. C., Miller, A. L. and Fluck, R. A. (1995). Microtubule arrays during ooplasmic segregation in medaka. Biological Bulletin 188: 136-145.

Fishman, H.M., Krause, T.L., Miller, A.L. and Bittner, G.D. (1995).  Retardation of the spread of extracellular Ca2+ into transected, unsealed squid giant axons. Biological Bulletin 189(2):208-9. [PubMed]

Fluck, R. A., Miller, A. L., Abraham, V. C. and Jaffe, L. F. (1994). Calcium buffer injections inhibit ooplasmic segregation in medaka. Biological Bulletin 186: 254-262.

Miller, B., Chauhan, A., Jaffe, L.F. and Miller, A.L. (1994).  Oscillations in free [Ca2+]i during early cell division cycles in Xenopus laevis embryos. Biological Bulletin 187(2):239-40. [PubMed]

Miller, A.L., Galione, A., Karplus, E. and Jaffe, L.F. (1993).  Mechanically-induced calcium release from Xenopus cell cycle extracts. Biol. Bull. 185: 290-292.

Miller, A.L., Fluck, R.A., McLaughlin, J.A. and Jaffe, L.F. (1993).  Calcium buffer injections inhibit cytokinesis in Xenopus eggs. J. Cell Science. 106: 523-534. [PubMed]

Eckberg, W.R., Miller, A.L., Short, L.G. and Jaffe, L.F.  (1993).  Calcium pulses during the activation of a protostome egg.  Biological Bulletin  185:289-290

Miller, A.L., Galione, A., Karplus, E. and Jaffe, L.F. (1993).  Mechanically induced calcium release from Xenopus cell cycle extracts.  Biological Bulletin 185: 290-292

Rossi, D.J., Kinney, G.A., Karplus, E., Miller, A.L., Jaffe, L.F. and Slate, N.T. (1993).  Fluorescence imaging of NMDA receptor-activated calcium influx in granule cells in thin cerebellar slices. Biological Bulletin  185: 295-296.

Abraham, V.C., Miller, A.L., Jaffe, L.F. and Fluck, R.A.  (1993).  Cytoplasmic microtubule arrays in Oryzias latipes (Medaka) eggs during ooplasmic segregation. Biological Bulletin 185: 305-306.

Browne, C.L., Miller, A.L., Palazzo, R.E. and Jaffe L.F. (1992).  On the calcium pulse during nuclear envelope breakdown (NEB) in sea urchin eggs. Biological Bulletin 183: 370-371.

Miller, A.L., Fluck, R.A. and Jaffe, L. F.  (1992).  Cell cycle contraction waves in Xenopus are suppressed by injecting calcium buffers.  Biological Bulletin 183: 368-369.

Fluck, R.A., Miller, A.L. and Jaffe, L.F. (1992).  High calcium zones at the poles of developing medaka eggs. Biological Bulletin 183: 70-77.

Fluck, R.A., Abraham, V.C., Miller, A.L. and Jaffe, L.F.  (1992).  Calcium buffer injections block ooplasmic segregation in Oryzias latipes (medaka) eggs. Biological Bulletin 183: 371-372.

Jaffe, L.F., Miller, A.L. and Fluck, R.A.  (1991).  A region of steady high calcium at the vegetal pole of medaka eggs.Biological Bulletin 181: 343-344.

Wang, R., Wu, L., Miller, A.L., Arnold, J.M. and Jaffe, L.F.  (1991)  KCl-induced calcium rise in squid eggs: Measurement of Fura-2 fluorescence. Biological Bulletin 181: 348-349.

Woodruff, R. I., Miller, A. L. and Jaffe L. F.  (1991).  Differences in free calcium concentration between oocytes and nurse cells revealed by corrected aequorin luminescence.Biological Bulletin 181: 349-350.

McLaughlin, J.A., Miller, A.L., Fluck, R.A. and Jaffe, L.F. (1991).  Calcium buffer injections block cytokinesis in Xenopus eggs.  Biological Bulletin 181: 345.

Fluck, R.A., Miller, A.L. and Jaffe L.F.  (1991).  Calcium waves accompany contraction waves in the Oryzias latipes (medaka) blastoderm. Biological Bulletin 181: 352.

Miller, A.L., Smith, P.J.S., Rainville, C.A., Shimomura, O. Strumwasser, F. and Jaffe L.F.  (1991).  Imaging free calcium in cultured Aplysia bag bell neurons.  Biological Bulletin 181: 325.

Fluck, R.A., Miller, A.L. and Jaffe, L.F. (1991). Slow calcium waves accompany cytokinesis in medaka fish eggs. J. Cell Biol. 115: 1259-1265. [PubMed]

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